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Original Article
Clinical considerations of acute leukemia or transient myeloprolifo- rative disorder in Down syndrome.
Eun Sil Dong, Sung Hee Jang, Hong Hoe Koo, Hye Lim Jung, Hee Young Shin, Hyo Seop Ahn
Clin Exp Pediatr. 1991;34(1):74-82.   Published online January 31, 1991
Children with Down syndrome have an increased incidence of acute leukemia. Infants with Down syndrome are also at risk of developing a transient myeloproliferative disorder indistinguishable from acute nonlymphocytic leukemia (ANLL) except by its eventual clinical recovery. We observed 11 patients with acute leukemia or transient myeloproliferative disorder in Down syndrome who had admitted to the Departmetn of Pediatrics, Seoul National University Children’s Hospital,...
A case of Second Malignant Neoplasm Complicating Hodgkin's Disease in Remission.
Hong Hoe Koo, Jong Woon Choi, Sang Oh Na, Il Soo Ha, Hee Young Shin, Hyo Seop Ahn, Yeon Lim Suh, Chul Woo Kim, Je Geun Chi
Clin Exp Pediatr. 1990;33(4):564-572.   Published online April 30, 1990
Recent advances in the treatment of cancer have resulted in increased survival and possible cure for many malignant disorders, particularly childhood cancers. There has been a marked improvement in the treatment of childhood Hodgkin’s disease, and five-year survival rates for even advanced stages of Hodgkin’s disease approach or exceed more than 75% with modern treatment policies. However, successful therapy in childhood cancer is frequently...
A case of congenital dyserythropoietic Anemia.
Sang Oh Na, Seong Hoon Ha, Hong Hoe Koo, Hee Young Shin, Il Soo Ha, Hyo Seop Ahn, Doek Ja Oh, Myoung Hee Park
Clin Exp Pediatr. 1990;33(3):410-415.   Published online March 31, 1990
The congenital dyserythropoietic anemia refers to a group of hereditary disorders of erythropoiesis characterized by ineffective erythropoiesis, multinuclearity of erythroblasts, and secondary hemo- chromatosis. The authors report a case of anemia in a 4 month-old girl whose bone marrow showed dyserythropoietic features. A brief review of referential literatures was made.
A Case of Mucinous Cystadenocarcinoma in a Premenarchal Girl.
Hong Hoe Koo, Sang Oh Na, In Sang Jeon, Hyo Seop Ahn, Wan Suk Park, Suk Koo Lee, Kwi Won Park, Chong Jai Kim, Je Geun Chi
Clin Exp Pediatr. 1990;33(1):124-128.   Published online January 31, 1990
In childhood, cancer of the ovary is highly unusual. It is responsible for only 1—2% of cancers found in patients under the age of 17. The frequency with which the various histologic types of ovarian neoplasm occur in childhood differs from that in adults. Epithelial tumors account for 70% to 80% of ovarian neoplasms in adults but only 20% in patients less than...
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